CYP2W1 antibody (Internal Region)

Catalog No. ABIN6258069

Product Details anti-CYP2W1 Antibody

Target: CYP2W1 (Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 (CYP2W1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2W1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Cytochrome P450 2W1 Antibody detects endogenous levels of total Cytochrome P450 2W1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 2W1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CYP2W1

Target: CYP2W1 (Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 (CYP2W1))

Alternative Name: CYP2W1 (CYP2W1 Products)

Synonyms: Gm455 antibody, cytochrome P450 family 2 subfamily W member 1 antibody, cytochrome P450, family 2, subfamily W, polypeptide 2 antibody, cytochrome P450, family 2, subfamily W, polypeptide 1 antibody, cytochrome P450, family 2, subfamily w, polypeptide 1 antibody, CYP2W1 antibody, CYP2W2 antibody, Cyp2w1 antibody

Background:

Description: Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Active also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743).

Gene: CYP2W1

Molecular Weight: 55 kDa

Gene ID: 54905

UniProt: Q8TAV3