CYP7A1 antibody (Internal Region)

Catalog No. ABIN6258082

Product Details anti-CYP7A1 Antibody

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP7A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: Cytochrome P450 7A1 Antibody detects endogenous levels of total Cytochrome P450 7A1.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 7A1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CYP7A1

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Alternative Name: CYP7A1 (CYP7A1 Products)

Synonyms: CP7A antibody, CYP7 antibody, CYPVII antibody, CHAP antibody, CYP7S1 antibody, cyp7a1a antibody, zgc:63920 antibody, cytochrome P450 family 7 subfamily A member 1 antibody, cytochrome P450, family 7, subfamily a, polypeptide 1 antibody, cytochrome P450, family 7, subfamily A, polypeptide 1 antibody, cholesterol 7-alpha-hydroxylase antibody, CYP7A1 antibody, Cyp7a1 antibody, cyp7a1 antibody

Background:

Description: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.

Gene: CYP7A1

Molecular Weight: 58 kDa

Gene ID: 1581

UniProt: P22680

Pathways: Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha