GPR52 antibody (Internal Region)
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- Target See all GPR52 Antibodies
- GPR52 (G Protein-Coupled Receptor 52 (GPR52))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GPR52 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- GPR52 Antibody detects endogenous levels of total GPR52.
- Predicted Reactivity
- Pig,Bovine,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GPR52, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GPR52 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- GPR52 (G Protein-Coupled Receptor 52 (GPR52))
- Alternative Name
- GPR52 (GPR52 Products)
- Synonyms
- GPR52 antibody, EG620246 antibody, G protein-coupled receptor 52 antibody, GPR52 antibody, Gpr52 antibody
- Background
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Description: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).
Gene: GPR52
- Molecular Weight
- 41 kDa,
- Gene ID
- 9293
- UniProt
- Q9Y2T5
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