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GPR52 antibody (Internal Region)

GPR52 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258184
  • Target See all GPR52 Antibodies
    GPR52 (G Protein-Coupled Receptor 52 (GPR52))
    Binding Specificity
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 33
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 33
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    This GPR52 antibody is un-conjugated
    Application
    • 23
    • 22
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    GPR52 Antibody detects endogenous levels of total GPR52.
    Predicted Reactivity
    Pig,Bovine,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GPR52, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GPR52 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    GPR52 (G Protein-Coupled Receptor 52 (GPR52))
    Alternative Name
    GPR52 (GPR52 Products)
    Synonyms
    GPR52 antibody, EG620246 antibody, G protein-coupled receptor 52 antibody, GPR52 antibody, Gpr52 antibody
    Background

    Description: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).

    Gene: GPR52

    Molecular Weight
    41 kDa,
    Gene ID
    9293
    UniProt
    Q9Y2T5
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