SARNP antibody (Internal Region)

Catalog No. ABIN6258229

Product Details anti-SARNP Antibody

Target: SARNP (SAP Domain Containing Ribonucleoprotein (SARNP))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARNP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: CIP29 Antibody detects endogenous levels of total CIP29.

Predicted Reactivity: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CIP29, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SARNP

Target: SARNP (SAP Domain Containing Ribonucleoprotein (SARNP))

Alternative Name: SARNP (SARNP Products)

Synonyms: CIP29 antibody, HCC1 antibody, HSPC316 antibody, THO1 antibody, 1110005A23Rik antibody, Cip29 antibody, RGD1305692 antibody, cip29 antibody, 1110005a23rik antibody, wu:fb11c11 antibody, zgc:109957 antibody, SAP domain containing ribonucleoprotein antibody, SAP domain containing ribonucleoprotein S homeolog antibody, SARNP antibody, Sarnp antibody, sarnp antibody, sarnp.S antibody

Background:

Description: Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form. Specifically binds to scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

Gene: SARNP

Molecular Weight: 30 kDa

Gene ID: 84324

UniProt: P82979