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PHLDA3 antibody (C-Term)

PHLDA3 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258301
  • Target See all PHLDA3 Antibodies
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 21
    • 6
    • 6
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 18
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 19
    • 2
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHLDA3 antibody is un-conjugated
    Application
    • 10
    • 8
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificity
    PHLDA3 Antibody detects endogenous levels of total PHLDA3.
    Predicted Reactivity
    Pig,Rabbit
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PHLDA3, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PHLDA3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Alternative Name
    PHLDA3 (PHLDA3 Products)
    Synonyms
    TIH1 antibody, Tih1 antibody, si:dz182n13.5 antibody, zgc:92333 antibody, pleckstrin homology like domain family A member 3 antibody, pleckstrin homology like domain, family A, member 3 antibody, pleckstrin homology-like domain, family A, member 3 antibody, PHLDA3 antibody, Phlda3 antibody, phlda3 antibody
    Background

    Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.

    Gene: PHLDA3

    Molecular Weight
    14 kDa
    Gene ID
    23612
    UniProt
    Q9Y5J5
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