CENPI antibody (Internal Region)

Catalog No. ABIN6258411

Product Details anti-CENPI Antibody

Target: CENPI (Centromere Protein I (CENPI))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: CENPI Antibody detects endogenous levels of total CENPI.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CENPI, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CENPI

Target: CENPI (Centromere Protein I (CENPI))

Alternative Name: CENPI (CENPI Products)

Synonyms: im:7159077 antibody, wu:fi32d01 antibody, CENP-I antibody, FSHPRH1 antibody, LRPR1 antibody, Mis6 antibody, AI504163 antibody, Fshprh1 antibody, RNALRP antibody, centromere protein I antibody, CENPI antibody, cenpi antibody, Cenpi antibody

Background:

Description: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone.

Gene: CENPI

Molecular Weight: 87 kDa

Gene ID: 2491

UniProt: Q92674