GFR antibody (C-Term)

Catalog No. ABIN6258443

Product Details anti-GFR Antibody

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: RAPGEF5 Antibody detects endogenous levels of total RAPGEF5.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAPGEF5, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GFR

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Alternative Name: RAPGEF5 (RAPGEF5 Products)

Synonyms: GFR antibody, MR-GEF antibody, REPAC antibody, 4932413M22 antibody, C86120 antibody, D030051B22Rik antibody, Mrgef antibody, mKIAA0277 antibody, mmr-gef antibody, RGD1562891 antibody, rMR-GEF antibody, MGC154311 antibody, Rap guanine nucleotide exchange factor 5 antibody, Rap guanine nucleotide exchange factor (GEF) 5 antibody, Rap guanine nucleotide exchange factor 5 S homeolog antibody, RAPGEF5 antibody, Rapgef5 antibody, rapgef5.S antibody

Background:

Description: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.

Gene: RAPGEF5

Molecular Weight: 60 kDa

Gene ID: 9771

UniProt: Q92565

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, Hepatitis C