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Fibrinogen beta Chain antibody (C-Term)

FGB Reactivity: Human, Mouse WB, IHC, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258456
  • Target See all Fibrinogen beta Chain (FGB) Antibodies
    Fibrinogen beta Chain (FGB)
    Binding Specificity
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 56
    • 16
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 55
    • 14
    • 1
    Rabbit
    Clonality
    • 56
    • 14
    Polyclonal
    Conjugate
    • 37
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Fibrinogen beta Chain antibody is un-conjugated
    Application
    • 50
    • 25
    • 22
    • 11
    • 9
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    FGB Antibody detects endogenous levels of total FGB.
    Predicted Reactivity
    Zebrafish,Bovine,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FGB, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product FGB Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Fibrinogen beta Chain (FGB)
    Alternative Name
    FGB (FGB Products)
    Synonyms
    FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody
    Background

    Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

    Gene: FGB

    Molecular Weight
    56 kDa
    Gene ID
    2244
    UniProt
    P02675
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