SPIC antibody (Internal Region)

Catalog No. ABIN6258474

Product Details anti-SPIC Antibody

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPIC antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SPIC Antibody detects endogenous levels of total SPIC.

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SPIC, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SPIC

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Alternative Name: SPIC (SPIC Products)

Synonyms: SPI-C antibody, AU019198 antibody, C76795 antibody, Prf antibody, Spi-C antibody, zgc:101790 antibody, spi-c antibody, spic antibody, Spi-C transcription factor antibody, transcription factor Spi-C-like antibody, Spi-C transcription factor (Spi-1/PU.1 related) antibody, Spi-C transcription factor (Spi-1/PU.1 related) S homeolog antibody, SPIC antibody, LOC100349167 antibody, Spic antibody, spic antibody, spic.S antibody

Background:

Description: Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).

Gene: SPIC

Molecular Weight: 29 kDa

Gene ID: 121599

UniProt: Q8N5J4