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CYP4V2 antibody (Internal Region)

CYP4V2 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6258485
  • Target See all CYP4V2 Antibodies
    CYP4V2 (Cytochrome P450, Family 4, Subfamily V, Polypeptide 2 (CYP4V2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 29
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 2
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP4V2 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Cytochrome P450 4V2 Antibody detects endogenous levels of total Cytochrome P450 4V2.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Cytochrome P450 4V2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    CYP4V2 (Cytochrome P450, Family 4, Subfamily V, Polypeptide 2 (CYP4V2))
    Alternative Name
    CYP4V2 (CYP4V2 Products)
    Synonyms
    BCD antibody, CYP4AH1 antibody, CYP4V antibody, bcd antibody, cyp4ah1 antibody, MGC147146 antibody, cytochrome P450 family 4 subfamily V member 2 antibody, cytochrome P450 family 4 subfamily V member 2 S homeolog antibody, cytochrome P450, family 4, subfamily V, polypeptide 2 antibody, cytochrome P450, family 4, subfamily v, polypeptide 2 antibody, CYP4V2 antibody, cyp4v2.S antibody, cyp4v2 antibody
    Background

    Description: Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592). Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592). Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592).

    Gene: CYP4V2

    Molecular Weight
    61 kDa
    Gene ID
    285440
    UniProt
    Q6ZWL3
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