GZMM antibody (Internal Region)

Catalog No. ABIN6258836

Product Details anti-GZMM Antibody

Target: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: GZMM Antibody detects endogenous levels of total GZMM.

Predicted Reactivity: Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GZMM, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for GZMM

Target: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Alternative Name: GZMM (GZMM Products)

Synonyms: LMET1 antibody, MET1 antibody, Lmet1 antibody, MMET-1 antibody, granzyme M antibody, granzyme M (lymphocyte met-ase 1) antibody, LOC100136381 antibody, GZMM antibody, Gzmm antibody

Background:

Description: Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Gene: GZMM

Molecular Weight: 28 kDa

Gene ID: 3004

UniProt: P51124