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IKZF4 antibody (C-Term)

IKZF4 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259025
  • Target See all IKZF4 Antibodies
    IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
    Binding Specificity
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 27
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 21
    • 5
    • 1
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IKZF4 antibody is un-conjugated
    Application
    • 18
    • 8
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    IKZF4 Antibody detects endogenous levels of total IKZF4.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IKZF4, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IKZF4 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
    Alternative Name
    IKZF4 (IKZF4 Products)
    Synonyms
    A630026H08Rik antibody, Eos antibody, Zfpn1a4 antibody, Znfn1a4 antibody, EOS antibody, ZNFN1A4 antibody, IKAROS family zinc finger 4 antibody, Ikzf4 antibody, IKZF4 antibody
    Background

    Description: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity).

    Gene: IKZF4

    Molecular Weight
    64 kDa
    Gene ID
    64375
    UniProt
    Q9H2S9
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