SH3G2 antibody (Internal Region)

Catalog No. ABIN6259026

Product Details anti-SH3G2 Antibody

Target: SH3G2 (Endophilin-A1 (SH3G2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3G2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SH3GL2 Antibody detects endogenous levels of total SH3GL2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SH3GL2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SH3G2

Target: SH3G2 (Endophilin-A1 (SH3G2))

Alternative Name: SH3GL2 (SH3G2 Products)

Synonyms: CNSA2 antibody, EEN-B1 antibody, SH3D2A antibody, SH3P4 antibody, 9530001L19Rik antibody, AI120490 antibody, AW555077 antibody, B930049H17Rik antibody, SH3PA antibody, Sh3d2a antibody, Sh3p4 antibody, SH3 domain containing GRB2 like 2, endophilin A1 antibody, SH3-domain GRB2-like 2 antibody, SH3GL2 antibody, Sh3gl2 antibody

Background:

Description: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.

Gene: SH3GL2

Molecular Weight: 39 kDa

Gene ID: 6456

UniProt: Q99962

Pathways: Neurotrophin Signaling Pathway, EGFR Downregulation