SRCIN1 antibody (Internal Region)

Catalog No. ABIN6259194

Product Details anti-SRCIN1 Antibody

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRCIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: SNIP Antibody detects endogenous levels of total SNIP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SNIP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SRCIN1

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Alternative Name: SRCIN1 (SRCIN1 Products)

Synonyms: P140 antibody, SNIP antibody, mKIAA1684 antibody, p140Cap antibody, Snip antibody, si:ch211-278a6.1 antibody, SRC kinase signaling inhibitor 1 antibody, si:ch211-278a6.1 antibody, SRCIN1 antibody, Srcin1 antibody

Background:

Description: Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.

Gene: SRCIN1

Molecular Weight: 112 kDa

Gene ID: 80725

UniProt: Q9C0H9