N4BP1 antibody (Internal Region)

Catalog No. ABIN6259305

Product Details anti-N4BP1 Antibody

Target: N4BP1 (NEDD4 Binding Protein 1 (N4BP1))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This N4BP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: N4BP1 Antibody detects endogenous levels of total N4BP1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human N4BP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for N4BP1

Target: N4BP1 (NEDD4 Binding Protein 1 (N4BP1))

Alternative Name: N4BP1 (N4BP1 Products)

Synonyms: AI481586 antibody, C81621 antibody, RGD1305179 antibody, wu:fi03b05 antibody, zgc:66437 antibody, NEDD4 binding protein 1 antibody, Nedd4 binding protein 1 antibody, nedd4 binding protein 1 antibody, nedd4 binding protein 1 L homeolog antibody, N4BP1 antibody, N4bp1 antibody, n4bp1 antibody, n4bp1.L antibody

Background:

Description: Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).

Gene: N4BP1

Molecular Weight: 100 kDa

Gene ID: 9683

UniProt: O75113