SPINK5 antibody (N-Term)

Catalog No. ABIN6259449

Product Details anti-SPINK5 Antibody

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPINK5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: SPINK5 Antibody detects endogenous levels of total SPINK5.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SPINK5, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SPINK5

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Alternative Name: SPINK5 (SPINK5 Products)

Synonyms: LEKTI antibody, LETKI antibody, NETS antibody, NS antibody, VAKTI antibody, 2310065D10Rik antibody, AV238912 antibody, LEKT1 antibody, LETK1 antibody, VAKT1 antibody, serine peptidase inhibitor, Kazal type 5 antibody, Spink5 antibody, SPINK5 antibody

Background:

Description: Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a  pH -dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.

Gene: SPINK5

Molecular Weight: 121 kDa

Gene ID: 11005

UniProt: Q9NQ38