ACOX1 antibody (Internal Region)

Catalog No. ABIN6259734

Product Details anti-ACOX1 Antibody

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: ACOX1 Antibody detects endogenous levels of total ACOX1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ACOX1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Alternative Name: ACOX1 (ACOX1 Products)

Synonyms: zgc:92584 antibody, wu:fb59h12 antibody, zgc:114033 antibody, aco antibody, acox antibody, ACOX antibody, PALMCOX antibody, SCOX antibody, RATACOA1 antibody, AOX antibody, Acox antibody, D130055E20Rik antibody, Paox antibody, PCOX1 antibody, acyl-CoA oxidase 1 antibody, acyl-CoA oxidase 1, palmitoyl antibody, acyl-CoA oxidase 1, palmitoyl L homeolog antibody, acyl-Coenzyme A oxidase 1, palmitoyl antibody, ACOX1 antibody, acox1 antibody, acox1.L antibody, Acox1 antibody

Background:

Description: Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25 % more active against 1,16-hexadecanodioyl-CoA.

Gene: ACOX1

Molecular Weight: 50 kDa

Gene ID: 51

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process