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AFF4 antibody (C-Term)

AFF4 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259815
  • Target See all AFF4 Antibodies
    AFF4 (AF4/FMR2 Family, Member 4 (AFF4))
    Binding Specificity
    • 15
    • 15
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 62
    • 14
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 57
    • 5
    Rabbit
    Clonality
    • 60
    • 2
    Polyclonal
    Conjugate
    • 27
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AFF4 antibody is un-conjugated
    Application
    • 32
    • 26
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    AFF4 Antibody detects endogenous levels of total AFF4.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human AFF4, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product AFF4 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    AFF4 (AF4/FMR2 Family, Member 4 (AFF4))
    Alternative Name
    AFF4 (AFF4 Products)
    Synonyms
    AFF4 antibody, RA_m002_jsmFBA6Br antibody, AF5Q31 antibody, MCEF antibody, Alf4 antibody, Laf4l antibody, AF4/FMR2 family member 4 L homeolog antibody, AF4/FMR2 family member 4 antibody, AF4/FMR2 family, member 4 antibody, aff4.L antibody, AFF4 antibody, aff4 antibody, Aff4 antibody
    Background

    Description: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

    Gene: AFF4

    Molecular Weight
    127kDa
    Gene ID
    27125
    UniProt
    Q9UHB7
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