Angiomotin antibody (Internal Region)

Catalog No. ABIN6259913

Product Details anti-Angiomotin Antibody

Target: Angiomotin (AMOT)

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiomotin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: AMOT Antibody detects endogenous levels of total AMOT.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AMOT, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Angiomotin

Target: Angiomotin (AMOT)

Alternative Name: AMOT (AMOT Products)

Synonyms: C81439 antibody, CAG-2 antibody, D0Kist1 antibody, E230009N18Rik antibody, Sii6 antibody, mKIAA1071 antibody, RGD1564027 antibody, si:dkey-13f9.6 antibody, wu:fj21a07 antibody, angiomotin antibody, microRNA 4329 antibody, AMOT antibody, Amot antibody, MIR4329 antibody, amot antibody

Background:

Description: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Gene: AMOT

Molecular Weight: 118kDa

Gene ID: 154796

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size