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TFAP2A antibody

TFAP2A Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259961
  • Target See all TFAP2A Antibodies
    TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
    Reactivity
    • 56
    • 20
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 39
    • 17
    • 3
    Rabbit
    Clonality
    • 41
    • 18
    Polyclonal
    Conjugate
    • 35
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TFAP2A antibody is un-conjugated
    Application
    • 44
    • 29
    • 11
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    AP-2 Antibody detects endogenous levels of AP-2
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human AP-2
    Isotype
    IgG
    Top Product
    Discover our top product TFAP2A Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Yang, Wei, Song, Cai, Zhou, Peng, Jiang, Peng: "E4BP4 mediates glucocorticoid-regulated adipogenesis through COX2." in: Molecular and cellular endocrinology, Vol. 450, pp. 43-53, (2018) (PubMed).

  • Target
    TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
    Alternative Name
    AP-2 (TFAP2A Products)
    Synonyms
    TFAP2A antibody, Ap-2 antibody, AP-2 antibody, AP-2alpha antibody, AP2TF antibody, BOFS antibody, TFAP2 antibody, ap2 antibody, xap2 antibody, XAP-2 antibody, ap2tf antibody, tfap2 antibody, ap-2alpha antibody, tfap2alpha antibody, cb93 antibody, fb83f04 antibody, fc31a07 antibody, wu:fb83f04 antibody, wu:fc31a07 antibody, tfap2a-a antibody, tcfap2a antibody, ap2a antibody, AP2alpha antibody, Ap2 antibody, Ap2tf antibody, Tcfap2a antibody, AP2 antibody, transcription factor AP-2 alpha antibody, transcription factor AP-2 antibody, tto transcription factor AP-2 alpha antibody, to transcription factor AP-2 alpha L homeolog antibody, to transcription factor AP-2 alpha S homeolog antibody, Transcription factor AP-2 alpha antibody, transcription factor AP-2, alpha antibody, TFAP2A antibody, LOC100302602 antibody, tfap2a antibody, tfap2a.L antibody, tfap2a.S antibody, ap2a antibody, Tfap2a antibody
    Background

    Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

    Gene: TFAP2A

    Molecular Weight
    49kDa
    Gene ID
    7020
    UniProt
    P05549, Q92481
    Pathways
    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism
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