BAZ1B antibody (Internal Region)
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- Target See all BAZ1B Antibodies
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BAZ1B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- BAZ1B Antibody detects endogenous levels of total BAZ1B.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human BAZ1B, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product BAZ1B Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
- Alternative Name
- BAZ1B (BAZ1B Products)
- Synonyms
- BAZ1B antibody, wstf antibody, wbscr9 antibody, wbscr10 antibody, LOC100220420 antibody, WBSCR10 antibody, WBSCR9 antibody, WSTF antibody, C87820 antibody, Wbscr9 antibody, fi60d02 antibody, im:7137554 antibody, wu:fi60d02 antibody, bromodomain adjacent to zinc finger domain 1B antibody, bromodomain adjacent to zinc finger domain, 1B antibody, bromodomain adjacent to zinc finger domain 1B S homeolog antibody, BAZ1B antibody, baz1b antibody, Baz1b antibody, baz1b.S antibody
- Background
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Description: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.
Gene: BAZ1B
- Molecular Weight
- 185 kDa
- Gene ID
- 9031
- UniProt
- Q9UIG0
- Pathways
- Nuclear Hormone Receptor Binding, Chromatin Binding
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