CABIN1 antibody (Internal Region)

Catalog No. ABIN6260386

Product Details anti-CABIN1 Antibody

Target: CABIN1 (Calcineurin Binding Protein 1 (CABIN1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CABIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: CABIN1 Antibody detects endogenous levels of total CABIN1.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CABIN1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CABIN1

Target: CABIN1 (Calcineurin Binding Protein 1 (CABIN1))

Alternative Name: CABIN1 (CABIN1 Products)

Synonyms: CABIN1 antibody, CAIN antibody, PPP3IN antibody, Cain antibody, A330070M20Rik antibody, Ppp3in antibody, calcineurin binding protein 1 antibody, CABIN1 antibody, cabin1 antibody, Cabin1 antibody

Background:

Description: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.

Gene: CABIN1

Molecular Weight: 246kDa

Gene ID: 23523

UniProt: Q9Y6J0