CAPZA1 antibody (Internal Region)

Catalog No. ABIN6260455

Product Details anti-CAPZA1 Antibody

Target: CAPZA1 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 1 (CAPZA1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CAPZA1 Antibody detects endogenous levels of total CAPZA1.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CAPZA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CAPZA1

Target: CAPZA1 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 1 (CAPZA1))

Alternative Name: CAPZA1 (CAPZA1 Products)

Synonyms: CAPZA1 antibody, sb:cb852 antibody, si:dkey-16k6.1 antibody, wu:fb36c09 antibody, wu:fc85a01 antibody, wu:fj45f05 antibody, zK16K6.1 antibody, zgc:101755 antibody, cappa1 antibody, capz antibody, caz1 antibody, CAPPA1 antibody, CAPZ antibody, CAZ1 antibody, Cappa1 antibody, capza antibody, Capza antibody, capping actin protein of muscle Z-line alpha subunit 1 antibody, capping protein (actin filament) muscle Z-line, alpha 1b antibody, capping protein (actin filament) muscle Z-line, alpha 1 antibody, capping actin protein of muscle Z-line alpha subunit 1 L homeolog antibody, capza1 antibody, CAPZA1 antibody, capza1b antibody, Capza1 antibody, capza1.L antibody

Background:

Description: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions.

Gene: CAPZA1

Molecular Weight: 33kDa

Gene ID: 829

UniProt: P52907

Pathways: Regulation of Actin Filament Polymerization