CAPZA2 antibody (Internal Region)

Catalog No. ABIN6260456

Product Details anti-CAPZA2 Antibody

Target: CAPZA2 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 2 (CAPZA2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: CAPZA2 Antibody detects endogenous levels of total CAPZA2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CAPZA2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CAPZA2

Target: CAPZA2 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 2 (CAPZA2))

Alternative Name: CAPZA2 (CAPZA2 Products)

Synonyms: CAPPA2 antibody, CAPZ antibody, CAPZA2 antibody, 1110053K06Rik antibody, AW208808 antibody, Cappa2 antibody, CapZ antibody, cappa2 antibody, capza2 antibody, capping actin protein of muscle Z-line alpha subunit 2 antibody, F-actin-capping protein subunit alpha-2 antibody, capping protein (actin filament) muscle Z-line, alpha 2 antibody, capping actin protein of muscle Z-line alpha subunit 2 L homeolog antibody, CAPZA2 antibody, LOC100380720 antibody, Capza2 antibody, capza2.L antibody

Background:

Description: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

Gene: CAPZA2

Molecular Weight: 33kDa

Gene ID: 830

UniProt: P47755

Pathways: Regulation of Actin Filament Polymerization