CCBL1 antibody (Internal Region)

Catalog No. ABIN6260525

Product Details anti-CCBL1 Antibody

Target: CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: CCBL1/KAT1 Antibody detects endogenous levels of total CCBL1/KAT1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCBL1/KAT1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CCBL1

Target: CCBL1 (Cysteine-S-conjugate beta-Lyase (CCBL1))

Alternative Name: KYAT1 (CCBL1 Products)

Synonyms: 2010009K05Rik antibody, AI182306 antibody, Gtk antibody, Kat1 antibody, KatI antibody, GTK antibody, KAT1 antibody, KATI antibody, kynurenine aminotransferase 1 antibody, Kyat1 antibody, KYAT1 antibody

Background:

Description: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.

Gene: KYAT1

Molecular Weight: 48-50 kDa

Gene ID: 883

UniProt: Q16773