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CCR2 antibody (Internal Region)

CCR2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260555
  • Target See all CCR2 Antibodies
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Binding Specificity
    • 16
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 89
    • 43
    • 41
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 79
    • 9
    • 4
    • 1
    Rabbit
    Clonality
    • 74
    • 18
    • 1
    Polyclonal
    Conjugate
    • 43
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR2 antibody is un-conjugated
    Application
    • 41
    • 24
    • 24
    • 17
    • 13
    • 11
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    CCR2 Antibody detects endogenous levels of total CCR2.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CCR2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CCR2 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Alternative Name
    CCR2 (CCR2 Products)
    Synonyms
    CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody
    Background

    Description: Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels (By similarity). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).

    Gene: CCR2

    Molecular Weight
    42 kDa
    Gene ID
    729230
    UniProt
    P41597
    Pathways
    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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