CD320 antibody (Internal Region)

Catalog No. ABIN6260613

Product Details anti-CD320 Antibody

Target: CD320 (CD320 Molecule (CD320))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD320 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CD320 Antibody detects endogenous levels of total CD320.

Predicted Reactivity: Bovine,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CD320, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CD320

Target: CD320 (CD320 Molecule (CD320))

Alternative Name: CD320 (CD320 Products)

Synonyms: 8D6 antibody, 8D6A antibody, TCBLR antibody, 425O18-1 antibody, D17Ertd716e antibody, NG29 antibody, VLDL antibody, RGD1305860 antibody, TCblR antibody, CD320 molecule antibody, CD320 antigen antibody, CD320 antibody, Cd320 antibody

Background:

Description: Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213). Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed:10727470). Functions as costimulator to promote B cell responses to antigenic stimuli, promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed:11418631). CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed:11418631).

Gene: CD320

Molecular Weight: 29kDa

Gene ID: 51293

UniProt: Q9NPF0