CDCA7L antibody (Internal Region)

Catalog No. ABIN6260692

Product Details anti-CDCA7L Antibody

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA7L antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CDCA7L Antibody detects endogenous levels of total CDCA7L.

Predicted Reactivity: Pig,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDCA7L, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDCA7L

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Alternative Name: CDCA7L (CDCA7L Products)

Synonyms: ram2 antibody, MGC154777 antibody, BC006933 antibody, JPO2 antibody, R1 antibody, RAM2 antibody, RAPGEF5 antibody, cell division cycle associated 7 like antibody, cell division cycle associated 7 like L homeolog antibody, cell division cycle-associated 7-like protein antibody, CDCA7L antibody, cdca7l.L antibody, LOC100454683 antibody, Cdca7l antibody

Background:

Description: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways, May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Gene: CDCA7L

Molecular Weight: 52 kDa

Gene ID: 55536

UniProt: Q96GN5