CENPQ antibody (Internal Region)

Catalog No. ABIN6260758

Product Details anti-CENPQ Antibody

Target: CENPQ (Centromere Protein Q (CENPQ))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CENPQ Antibody detects endogenous levels of total CENPQ.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CENPQ, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CENPQ

Target: CENPQ (Centromere Protein Q (CENPQ))

Alternative Name: CENPQ (CENPQ Products)

Synonyms: C6orf139 antibody, CENP-Q antibody, 2610528M18Rik antibody, centromere protein Q antibody, CENPQ antibody, cenpq antibody, Cenpq antibody

Background:

Description: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (PubMed:16622420). Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores (PubMed:25395579).

Gene: CENPQ

Molecular Weight: 31 kDa

Gene ID: 55166

UniProt: Q7L2Z9