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CHI3L1 antibody (Internal Region)

CHI3L1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260804
  • Target See all CHI3L1 Antibodies
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    Binding Specificity
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 43
    • 29
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 41
    • 5
    • 1
    Rabbit
    Clonality
    • 41
    • 5
    • 1
    Polyclonal
    Conjugate
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHI3L1 antibody is un-conjugated
    Application
    • 36
    • 15
    • 13
    • 13
    • 10
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificity
    CHI3L1 Antibody detects endogenous levels of total CHI3L1.
    Predicted Reactivity
    Pig,Bovine,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CHI3L1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
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    Discover our top product CHI3L1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:100, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    Alternative Name
    CHI3L1 (CHI3L1 Products)
    Synonyms
    AW208766 antibody, Brp39 antibody, Gp39 antibody, ASRT7 antibody, CGP-39 antibody, GP-39 antibody, GP39 antibody, HC-gp39 antibody, HCGP-3P antibody, YKL-40 antibody, YKL40 antibody, YYL-40 antibody, hCGP-39 antibody, GP38K antibody, CLP-1 antibody, SPC-40 antibody, SPS-40 antibody, Chil1 antibody, BP40 antibody, MGP-40 antibody, chitinase-like 1 antibody, chitinase 3 like 1 antibody, chitinase 3-like 1 (cartilage glycoprotein-39) antibody, Chil1 antibody, CHI3L1 antibody, Chi3l1 antibody
    Target Type
    Viral Protein
    Background

    Description: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

    Gene: CHI3L1

    Molecular Weight
    43kD
    Gene ID
    1116
    UniProt
    P36222
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