CYP46A1 antibody

Catalog No. ABIN6261203

Product Details anti-CYP46A1 Antibody

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP46A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Cytochrome P450 46A1 Antibody detects endogenous levels of total Cytochrome P450 46A1

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 46A1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for CYP46A1

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Alternative Name: Cytochrome P450 46A1 (CYP46A1 Products)

Synonyms: CP46 antibody, CYP46 antibody, CYP46A1 antibody, zgc:109896 antibody, MGC147389 antibody, Cyp46 antibody, cytochrome P450 family 46 subfamily A member 1 antibody, cytochrome P450 family 46 subfamily A member 1 L homeolog antibody, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 antibody, cytochrome P450, family 46 antibody, cytochrome P450 46A1 antibody, cytochrome P450, family 46, subfamily a, polypeptide 1 antibody, cholesterol 24-hydroxylase antibody, cytochrome P450, family 46, subfamily A, polypeptide 1 antibody, CYP46A1 antibody, cyp46a1.L antibody, cyp46a1.1 antibody, cyp46a1 antibody, PTRG_08343 antibody, PTRG_09667 antibody, Cyp46a1 antibody, Sgly_1093 antibody

Background:

Description: Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.

Gene: CYP46A1

Molecular Weight: 57 kDa

Gene ID: 10858

UniProt: Q9Y6A2