DHRS11 antibody (Internal Region)

Catalog No. ABIN6261289

Product Details anti-DHRS11 Antibody

Target: DHRS11 (Dehydrogenase/reductase (SDR Family) Member 11 (DHRS11))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHRS11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: DHRS11 Antibody detects endogenous levels of total DHRS11.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DHRS11, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DHRS11

Target: DHRS11 (Dehydrogenase/reductase (SDR Family) Member 11 (DHRS11))

Alternative Name: DHRS11 (DHRS11 Products)

Synonyms: ARPG836 antibody, SDR24C1 antibody, RGD1307935 antibody, zgc:153028 antibody, wu:fb65d05 antibody, zgc:86722 antibody, dehydrogenase/reductase 11 antibody, dehydrogenase/reductase (SDR family) member 11 S homeolog antibody, dehydrogenase/reductase (SDR family) member 11 antibody, dehydrogenase/reductase (SDR family) member 11a antibody, dehydrogenase/reductase (SDR family) member 11b antibody, DHRS11 antibody, Dhrs11 antibody, dhrs11.S antibody, dhrs11 antibody, dhrs11a antibody, dhrs11b antibody

Background:

Description: Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.

Gene: DHRS11

Molecular Weight: 28 kDa

Gene ID: 79154

UniProt: Q6UWP2