DIO1 antibody (C-Term)

Catalog No. ABIN6261300

Product Details anti-DIO1 Antibody

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: DIO1 Antibody detects endogenous levels of total DIO1.

Predicted Reactivity: Pig,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DIO1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DIO1

Target: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Alternative Name: DIO1 (DIO1 Products)

Synonyms: 5DI antibody, TXDI1 antibody, ITDI1 antibody, D1 antibody, DIOI antibody, Deio1 antibody, cb685 antibody, zgc:92323 antibody, iodothyronine deiodinase 1 antibody, type I iodothyronine deiodinase-like antibody, deiodinase, iodothyronine, type I antibody, deiodinase, iodothyronine type 1 L homeolog antibody, DIO1 antibody, LOC100231867 antibody, Dio1 antibody, dio1.L antibody, dio1 antibody

Background:

Description: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

Gene: DIO1

Molecular Weight: 13 kDa, 29 kDa

Gene ID: 1733

UniProt: P49895

Pathways: Hormone Activity