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DMAP1 antibody (Internal Region)

DMAP1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261316
  • Target See all DMAP1 Antibodies
    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
    Binding Specificity
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 34
    • 13
    • 10
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 4
    • 4
    Rabbit
    Clonality
    • 31
    • 4
    Polyclonal
    Conjugate
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DMAP1 antibody is un-conjugated
    Application
    • 25
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    DMAP1 Antibody detects endogenous levels of total DMAP1.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human DMAP1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DMAP1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
    Alternative Name
    DMAP1 (DMAP1 Products)
    Synonyms
    Afu4g07380 antibody, T8I13.5 antibody, DNMAP1 antibody, DNMTAP1 antibody, EAF2 antibody, MEAF2 antibody, SWC4 antibody, zgc:55593 antibody, dnmap1 antibody, dnmtap1 antibody, eaf2 antibody, meaf2 antibody, swc4 antibody, 1500016M21Rik antibody, Dmtap1 antibody, mKIAA1425 antibody, DNA methyltransferase 1-associated protein DMAP1 antibody, DNA methyltransferase 1-associated protein 1 antibody, DNA methyltransferase 1 associated protein 1 antibody, myb-like transcription factor family protein antibody, DNA methyltransferase 1 associated protein 1 L homeolog antibody, AFUA_4G07380 antibody, NFIA_108840 antibody, ACLA_046700 antibody, CpipJ_CPIJ017959 antibody, Bm1_47540 antibody, PMAA_026820 antibody, AFLA_112450 antibody, TSTA_072020 antibody, BDBG_02603 antibody, AT2G47210 antibody, CpipJ_CPIJ007438 antibody, DMAP1 antibody, dmap1 antibody, dmap1.L antibody, Dmap1 antibody
    Background

    Description: Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

    Gene: DMAP1

    Molecular Weight
    53 kDa
    Gene ID
    55929
    UniProt
    Q9NPF5
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