EIF5A antibody (Internal Region)

Catalog No. ABIN6261503

Product Details anti-EIF5A Antibody

Target: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF5A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: EIF5A Antibody detects endogenous levels of total EIF5A.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EIF5A, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for EIF5A

Target: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Alternative Name: EIF5A (EIF5A Products)

Synonyms: EIF-5A antibody, EIF5A1 antibody, eIF5AI antibody, EIF5A antibody, zgc:55504 antibody, zgc:77429 antibody, wu:fb05b06 antibody, wu:fc23f04 antibody, wu:fc61c10 antibody, AA410058 antibody, D19Wsu54e antibody, Eif4d antibody, Eif5a1 antibody, eIF-4D antibody, eIF-5A antibody, eIF-5A-1 antibody, eIF-5A1 antibody, zgc:77099 antibody, wu:fb17e01 antibody, wu:fb63h04 antibody, wu:fk81e04 antibody, DDBDRAFT_0191442 antibody, DDBDRAFT_0218663 antibody, DDB_0191442 antibody, DDB_0218663 antibody, 1296 antibody, CG3186 antibody, Dmel\\CG3186 antibody, anon-EST:fe2H10 antibody, eIF5A antibody, eIF5a antibody, l(2)01296 antibody, EIF-5A1 antibody, NeIF-5A3 antibody, eif5a antibody, iff-2 antibody, eukaryotic translation initiation factor 5A antibody, eukaryotic translation initiation factor 5A2 antibody, eukaryotic translation initiation factor 5a antibody, putative eukaryotic initiation factor 5a antibody, CG3186 gene product from transcript CG3186-RB antibody, eukaryotic translation initiation factor 5A-1 antibody, eukaryotic translation initiation factor 5A L homeolog antibody, EIF5A antibody, eif5a2 antibody, Eif5a antibody, eif5a antibody, tif5A antibody, Tb11.03.0410 antibody, LOC5579111 antibody, EIF5A1 antibody, eIF-5A antibody, LOC107820748 antibody, eif5a.L antibody

Background:

Description: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Gene: EIF5A

Molecular Weight: 16kDa

Gene ID: 1984

UniProt: P63241

Pathways: Regulation of Muscle Cell Differentiation