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ELOVL1 antibody (Internal Region)

ELOVL1 Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261519
  • Target See all ELOVL1 Antibodies
    ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))
    Binding Specificity
    • 14
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 39
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 39
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 16
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELOVL1 antibody is un-conjugated
    Application
    • 26
    • 25
    • 5
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ELOVL1 Antibody detects endogenous levels of total ELOVL1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ELOVL1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ELOVL1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))
    Alternative Name
    ELOVL1 (ELOVL1 Products)
    Synonyms
    AA407424 antibody, BB151133 antibody, Ssc1 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 antibody, ELOVL fatty acid elongase 1 antibody, Elovl1 antibody, ELOVL1 antibody
    Background

    Description: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

    Gene: ELOVL1

    Molecular Weight
    35kDa
    Gene ID
    64834
    UniProt
    Q9BW60
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