ELOVL2 antibody (N-Term)

Catalog No. ABIN6261520

Product Details anti-ELOVL2 Antibody

Target: ELOVL2 (ELOVL Fatty Acid Elongase 2 (ELOVL2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: ELOVL2 Antibody detects endogenous levels of total ELOVL2.

Predicted Reactivity: Zebrafish,Horse,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ELOVL2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ELOVL2

Target: ELOVL2 (ELOVL Fatty Acid Elongase 2 (ELOVL2))

Alternative Name: ELOVL2 (ELOVL2 Products)

Synonyms: AI317360 antibody, Ssc2 antibody, SSC2 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 antibody, ELOVL fatty acid elongase 2 antibody, Elovl2 antibody, ELOVL2 antibody

Background:

Description: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Gene: ELOVL2

Molecular Weight: 35 kDa

Gene ID: 54898

UniProt: Q9NXB9