ESRRA antibody (Internal Region)
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- Target See all ESRRA Antibodies
- ESRRA (Estrogen-Related Receptor alpha (ESRRA))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ESRRA antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- ESRRA Antibody detects endogenous levels of total ESRRA.
- Predicted Reactivity
- Bovine,Horse,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ESRRA, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ESRRA Primary Antibody
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- Application Notes
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ESRRA (Estrogen-Related Receptor alpha (ESRRA))
- Alternative Name
- ESRRA (ESRRA Products)
- Synonyms
- err1 antibody, erra antibody, esrral antibody, erralpha antibody, nr3b1 antibody, MGC80854 antibody, ESRRA antibody, esrl1 antibody, LOC100125507 antibody, ERRalpha antibody, Err1 antibody, Estrra antibody, Nr3b1 antibody, Errra antibody, ERR1 antibody, ERRa antibody, ESRL1 antibody, NR3B1 antibody, ESTRRA antibody, estrogen-related receptor alpha antibody, estrogen related receptor alpha L homeolog antibody, estrogen related receptor alpha antibody, catsper channel auxiliary subunit zeta antibody, estrogen related receptor, alpha antibody, esrra antibody, esrra.L antibody, ESRRA antibody, LOC100125507 antibody, CATSPERZ antibody, Esrra antibody
- Background
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Description: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
Gene: ESRRA
- Molecular Weight
- ?55 kDa
- Gene ID
- 2101
- UniProt
- P11474
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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