SLC27A1 antibody (Internal Region)

Catalog No. ABIN6261687

Product Details anti-SLC27A1 Antibody

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC27A1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: FATP1 Antibody detects endogenous levels of total FATP1.

Predicted Reactivity: Bovine,Horse,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FATP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC27A1

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Alternative Name: SLC27A1 (FATP1 Products)

Synonyms: ACSVL5 antibody, FATP antibody, FATP1 antibody, Fatp antibody, FATP-1 antibody, FATP-1c antibody, solute carrier family 27 member 1 antibody, solute carrier family 27 (fatty acid transporter), member 1 antibody, SLC27A1 antibody, Slc27a1 antibody

Background:

Description: Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane (PubMed:28178239). Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism (By similarity).

Gene: SLC27A1

Molecular Weight: 65 kDa

Gene ID: 376497

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha