Fibulin 1 antibody (Internal Region)

Catalog No. ABIN6261690

Product Details anti-Fibulin 1 Antibody

Target: Fibulin 1 (FBLN1)

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: FBLN1 Antibody detects endogenous levels of total FBLN1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FBLN1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Fibulin 1

Target: Fibulin 1 (FBLN1)

Alternative Name: FBLN1 (FBLN1 Products)

Synonyms: fbln1 antibody, FBLN antibody, FIBL1 antibody, fbln1c antibody, fbln1d antibody, wu:fc52c06 antibody, MGC115035 antibody, fibulin 1 antibody, fibulin 1 L homeolog antibody, FBLN1 antibody, fbln1 antibody, Fbln1 antibody, fbln1.L antibody, CpipJ_CPIJ017419 antibody

Background:

Description: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.

Gene: FBLN1

Molecular Weight: 77 kDa

Gene ID: 2192

UniProt: P23142