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FBXO22 antibody (Internal Region)

FBXO22 Reactivity: Human WB, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261694
  • Target See all FBXO22 Antibodies
    FBXO22 (F-Box Protein 22 (FBXO22))
    Binding Specificity
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 18
    • 16
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 2
    Rabbit
    Clonality
    • 21
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This FBXO22 antibody is un-conjugated
    Application
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    FBXO22 Antibody detects endogenous levels of total FBXO22.
    Predicted Reactivity
    Bovine,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FBXO22, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product FBXO22 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    FBXO22 (F-Box Protein 22 (FBXO22))
    Alternative Name
    FBXO22 (FBXO22 Products)
    Synonyms
    FBXO22 antibody, DKFZp469L0535 antibody, fbxo22 antibody, MGC146708 antibody, si:busm1-132m23.3 antibody, FBX22 antibody, FISTC1 antibody, 0610033L19Rik antibody, 1600016C16Rik antibody, F-box protein 22 antibody, FBXO22 antibody, fbxo22 antibody, Fbxo22 antibody
    Background

    Description: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.

    Gene: FBXO22

    Molecular Weight
    45 kDa
    Gene ID
    26263
    UniProt
    Q8NEZ5
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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