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c-FOS antibody (N-Term)

c-Fos Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261783
  • Target See all c-FOS (c-Fos) Antibodies
    c-FOS (c-Fos) (c-Fos)
    Binding Specificity
    • 55
    • 26
    • 25
    • 25
    • 19
    • 16
    • 15
    • 15
    • 10
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 247
    • 154
    • 135
    • 13
    • 12
    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 200
    • 73
    • 8
    • 1
    Rabbit
    Clonality
    • 197
    • 84
    Polyclonal
    Conjugate
    • 112
    • 17
    • 15
    • 15
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    This c-FOS antibody is un-conjugated
    Application
    • 241
    • 80
    • 80
    • 76
    • 63
    • 40
    • 34
    • 26
    • 13
    • 12
    • 11
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Specificity
    C-Fos Antibody detects endogenous levels of total c-Fos.
    Predicted Reactivity
    Pig,Bovine,Horse,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human c-Fos, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    c-FOS (c-Fos) (c-Fos)
    Alternative Name
    FOS (c-Fos Products)
    Synonyms
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    Background

    Description: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Gene: FOS

    Molecular Weight
    50 kDa
    Gene ID
    2353
    UniProt
    P01100
    Pathways
    S100 Proteins
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