FSHR antibody (Internal Region)

Catalog No. ABIN6261821

Product Details anti-FSHR Antibody

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSHR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: FSHR Antibody detects endogenous levels of total FSHR.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FSHR, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FSHR

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Alternative Name: FSHR (FSHR Products)

Synonyms: FSHRO antibody, LGR1 antibody, ODG1 antibody, FSH-R antibody, eFSHR antibody, FSHRE antibody, fshr antibody, FSHR antibody, fshr-A antibody, GTHR-I antibody, zfGTHR-I antibody, LOC100304505 antibody, follicle stimulating hormone receptor antibody, follicle stimulating hormone receptor L homeolog antibody, follicle-stimulating hormone receptor antibody, FSHR antibody, fshr antibody, Fshr antibody, fshr.L antibody, Bm1_17785 antibody, LOC100304505 antibody

Background:

Description: Receptor for follicle-stimulating hormone or follitropin (PubMed:11847099, PubMed:24058690). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Induces cAMP production through the activation of PI3K-AKT and SRC-ERK1/2 signaling pathways (PubMed:24058690).

Gene: FSHR

Molecular Weight: 78 kDa

Gene ID: 2492

UniProt: P23945

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling