FUT2 antibody (Internal Region)

Catalog No. ABIN6261831

Product Details anti-FUT2 Antibody

Target: FUT2 (Fucosyltransferase 2 (Secretor Status Included) (FUT2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: FUT2 Antibody detects endogenous levels of total FUT2.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FUT2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FUT2

Target: FUT2 (Fucosyltransferase 2 (Secretor Status Included) (FUT2))

Alternative Name: FUT2 (FUT2 Products)

Synonyms: FUT2 antibody, ATFUT2 antibody, T18E12.12 antibody, T18E12_12 antibody, fucosyltransferase 2 antibody, B12QTL1 antibody, SE antibody, SEC2 antibody, Se2 antibody, sej antibody, Ftc antibody, Futb antibody, sec1 antibody, Fut2 antibody, fucosyltransferase 2 antibody, galactoside 2-alpha-L-fucosyltransferase 2 antibody, fucosyltransferase 2 (secretor status included) antibody, galactoside 2-L-fucosyltransferase antibody, FUT2 antibody, LOC722582 antibody, Fut2 antibody, RFT-II antibody

Background:

Description: Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids (PubMed:7876235). The resulting epitope plays a role in cell-cell interaction including host-microbe interaction (PubMed:12692541, PubMed:8018146). Mediates interaction with intestinal microbiota influencing its composition (PubMed:21625510, PubMed:24733310, PubMed:22068912). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:7876235).

Gene: FUT2

Molecular Weight: 39 kDa

Gene ID: 2524

UniProt: Q10981