GAS6 antibody (Internal Region)

Catalog No. ABIN6261888

Product Details anti-GAS6 Antibody

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: GAS6 Antibody detects endogenous levels of total GAS6.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GAS6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Alternative Name: GAS6 (GAS6 Products)

Synonyms: fj34a12 antibody, zgc:63860 antibody, wu:fj34a12 antibody, MGC68463 antibody, gas6 antibody, MGC83872 antibody, GAS6 antibody, Gas-6 antibody, AXLLG antibody, AXSF antibody, growth arrest specific 6 antibody, growth arrest-specific 6 antibody, growth arrest specific 6 L homeolog antibody, growth arrest specific 6 S homeolog antibody, GAS6 antibody, gas6 antibody, gas6.L antibody, gas6.S antibody, Gas6 antibody

Background:

Description: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Gene: GAS6

Molecular Weight: 79 kDa

Gene ID: 2621

UniProt: Q14393

Pathways: RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response