GANAB antibody (Internal Region)

Catalog No. ABIN6261982

Product Details anti-GANAB Antibody

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANAB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Glucosidase II alpha Antibody detects endogenous levels of total Glucosidase II alpha.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Glucosidase II alpha, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GANAB

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Alternative Name: GANAB (GANAB Products)

Synonyms: GANAB antibody, AU042638 antibody, G2an antibody, GluII antibody, mKIAA0088 antibody, G2AN antibody, GLUII antibody, glucosidase II alpha subunit antibody, glucosidase, alpha; neutral AB L homeolog antibody, alpha glucosidase 2 alpha neutral subunit antibody, GANAB antibody, ganab.L antibody, Ganab antibody

Background:

Description: Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia (PubMed:27259053).

Gene: GANAB

Molecular Weight: 107kDa

Gene ID: 23193

UniProt: Q14697