GPM6A antibody (Internal Region)

Catalog No. ABIN6262046

Product Details anti-GPM6A Antibody

Target: GPM6A (Glycoprotein M6A (GPM6A))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPM6A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: GPM6A Antibody detects endogenous levels of total GPM6A.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPM6A, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GPM6A

Target: GPM6A (Glycoprotein M6A (GPM6A))

Alternative Name: GPM6A (GPM6A Products)

Synonyms: GPM6 antibody, M6A antibody, Gpm6 antibody, M6a antibody, EMA antibody, GPM6A antibody, gpm6a antibody, MGC145278 antibody, DMbeta/M6a antibody, gpm6a-A antibody, wu:fj36c01 antibody, zgc:77575 antibody, DMbeta2 antibody, gm6a antibody, glycoprotein M6A antibody, glycoprotein m6a antibody, glycoprotein M6A L homeolog antibody, glycoprotein M6Aa antibody, glycoprotein M6Ab antibody, GPM6A antibody, Gpm6a antibody, gpm6a antibody, gpm6a.L antibody, gpm6aa antibody, gpm6ab antibody

Background:

Description: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), enhances internalization and recycling of mu-type opioid receptor.

Gene: GPM6A

Molecular Weight: 31 kDa

Gene ID: 2823

UniProt: P51674