GREM2 antibody (Internal Region)

Catalog No. ABIN6262080

Product Details anti-GREM2 Antibody

Target: GREM2 (Gremlin 2 (GREM2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GREM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: GREM2 Antibody detects endogenous levels of total GREM2.

Predicted Reactivity: Pig,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GREM2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GREM2

Target: GREM2 (Gremlin 2 (GREM2))

Alternative Name: GREM2 (GREM2 Products)

Synonyms: prdc antibody, zgc:112207 antibody, RGD1560008 antibody, Gremlin2 antibody, Prdc antibody, CKTSF1B2 antibody, DAND3 antibody, PRDC antibody, gremlin 2, DAN family BMP antagonist antibody, gremlin 2, DAN family BMP antagonist b antibody, gremlin 2, cysteine knot superfamily antibody, GREM2 antibody, grem2b antibody, grem2 antibody, Grem2 antibody

Background:

Description: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.

Gene: GREM2

Molecular Weight: 19 kDa

Gene ID: 64388

UniProt: Q9H772