HIST1H1C antibody (N-Term)

Catalog No. ABIN6262249

Product Details anti-HIST1H1C Antibody

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H1C antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: Histone H1.2 Antibody detects endogenous levels of total Histone H1.2.

Predicted Reactivity: Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Histone H1.2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HIST1H1C

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Alternative Name: HIST1H1C (HIST1H1C Products)

Synonyms: H1.2 antibody, H1C antibody, H1F2 antibody, H1s-1 antibody, 0610008C09Rik antibody, H1c antibody, H1f2 antibody, H1var1 antibody, His1a antibody, histone cluster 1 H1 family member c antibody, histone cluster 1, H1c antibody, HIST1H1C antibody, Hist1h1c antibody

Background:

Description: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Gene: HIST1H1C

Molecular Weight: 32-33 kDa

Gene ID: 3006

UniProt: P16403