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HOMER1 antibody (Internal Region)

HOMER1 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262337
  • Target See all HOMER1 Antibodies
    HOMER1 (Homer Homolog 1 (HOMER1))
    Binding Specificity
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 39
    • 21
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 34
    • 4
    • 1
    Rabbit
    Clonality
    • 36
    • 3
    Polyclonal
    Conjugate
    • 25
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOMER1 antibody is un-conjugated
    Application
    • 28
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    HOMER1 Antibody detects endogenous levels of total HOMER1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HOMER1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product HOMER1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    HOMER1 (Homer Homolog 1 (HOMER1))
    Alternative Name
    HOMER1 (HOMER1 Products)
    Synonyms
    HOMER antibody, HOMER1A antibody, HOMER1B antibody, HOMER1C antibody, SYN47 antibody, Ves-1 antibody, HOMER1 antibody, PSD-Zip45 antibody, homer1 antibody, zgc:100854 antibody, zgc:92844 antibody, HOMER1F antibody, Vesl-1 antibody, homer antibody, xhomer1 antibody, BEST:LD03829 antibody, CG11324 antibody, Dhom antibody, Dhomer antibody, Dm Homer antibody, Dmel\CG11324 antibody, Dvh antibody, Hom antibody, Homer antibody, LD03829 antibody, dhom antibody, homer scaffolding protein 1 antibody, homer scaffolding protein 1b antibody, homer scaffolding protein 1 L homeolog antibody, CG11324 gene product from transcript CG11324-RD antibody, HOMER1 antibody, Homer1 antibody, homer1b antibody, homer1.L antibody, homer antibody
    Background

    Description: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

    Gene: HOMER1

    Molecular Weight
    46-48 kDa
    Gene ID
    9456
    UniProt
    Q86YM7
    Pathways
    Skeletal Muscle Fiber Development
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